A női nemi hormonok koncentrációja és a testösszetétel életkori összefüggései

The main aims of the study were: (1) to reveal age patterns female sex hormone levels (17-β-estradiol, progesterone), quantitative ultrasound parameters (broadband attenuation, speed sound) and body composition components (fat-free mass, lean muscle bone mineral content, fat mass visceral area) in women aged 7 80 years; (2) define normal ranges for IBL 17-β-estradiol progesterone kits girls under 17 years age; (3) make recommendations on timing saliva collection premenarcheal girls; (4) analyse relationships between concentration 17-β-estradiol, skeletal system indicators adiposity according reproduction status; (5) evaluate associations with taking oral contraceptives (6) affected by gynaecological diseases comorbidities; (7) select a component determining its predictive factors; (8) estimate frequency X-chromosome loss identify determinants.
 In doctoral dissertation: levels, have been revealed (n=975); defined; made; status analysed; diseases, disorders comorbidities evaluated; has selected factors determined; X chromosome estimated determinants identified (n=50).
 Osteoporosis, obesity infertility are seemingly independent diseases. results dissertation that one their common points is abdominal obesity. premenopausal was negatively correlated area. Obese had lower level than non-obese women. As new we could confirm increased WHR reduced cells karyotype; malnutrition, excessive area risk developing osteoporosis women; overweight or obese women, WHR, smaller relative BMC having BMI, area; negative effect amount mass.
 highlighted importance both as factor loss. easy measure, inexpensive non-invasive way be informed about distribution fat. Based our can recommend reproductive status, physical activity into FRAX® calculator.